Neural Compass
Neural Compass
Podcast Description
Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com
Podcast Insights
Content Themes
The podcast covers a range of topics including advancements in AI and mental health care, the role of data in improving therapeutic relationships, and innovative treatment models. Episodes feature discussions like the impact of AI on therapy with guests such as Dr. Lyle Ungar, the importance of measurement-based care with Dr. Amber Childs, and strategies for addressing anxiety with Dr. Luana Marques, providing unique insights and practical tools.

If you work in mental health, invest in it, build in it, or just believe it deserves better than it is getting: Neural Compass is for you.
Filter episodes by category to find exactly what you’re looking for, from AI Meets the Clinic to Founders & Funders to Behavioral Science, right here: https://jiminihealth.com/podcast
Every two weeks, Jimini Health co-founder Mark Jacobstein sits down with the scientists, clinicians, and executives who are actually moving the field. The conversations go deep. The guests are the real thing.
Episodes have covered the clinical case for ketamine, the genomics of psychiatric diagnosis, what AI can and cannot do for behavioral health, and what it takes to reform mental healthcare from inside the system.
Guests have included former National Institute of Mental Health director Tom Insel, Yale psychiatry chair John Krystal, and researchers and executives at the frontier of behavioral health and AI.
What you will understand by the end:
- Why China is the most plausible explanation for America’s overdose reversal, and what the Canada data tells us
- Why Oregon failed where Portugal succeeded, and what the difference actually was
- Why the look on your friends’ faces does more to prevent addiction than any law ever has
- What AA gets right that the formal treatment system still hasn’t figured out
- Why GLP-1 drugs like Ozempic may be the next frontier in treating addiction
- Neural Compass is a podcast from Jimini Health, which builds clinically embedded AI for behavioral health. If you found this conversation valuable, please leave a rating or review on Apple Podcasts.
About the Guest
Keith shares how a chance meeting at a fast-food job led him to addiction research. He originally took the job because it paid better than flipping burgers. This moment started a career dedicated to understanding why the human brain chooses drugs over basic needs like food.
Recent data shows the largest decline in overdose deaths ever recorded in the United States. Keith explains that this drop happened because the drugs on the street became weaker and less available. This suggests that international pressure on drug production is actively saving lives.
Many people thought following Portugal’s path of changing drug laws would help the US West Coast. Keith explains that Oregon failed because it removed the pressure for people to seek treatment. Portugal still uses the law and social circles to guide people toward help.
Laws are important, but the opinions of friends and family often have a bigger impact on behavior. Keith points out that we care more about what our neighbors think than we do about getting a ticket. This social bond is a powerful tool for preventing drug use from getting out of control.
Programs like Alcoholics Anonymous provide a community that medical professionals alone cannot replace. Keith discusses how sharing stories and having peers who understand the struggle creates hope and accountability. It shows that there are many different paths to recovery.
Researchers are looking at how new medications for diabetes and weight loss can help stop drug cravings. Keith also highlights the importance of prevention for young people to stop addiction before it starts. He believes technology can now help us predict and prevent crises before they happen.

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