In this episode, we sit down with Dr. Mathijs Theelen, a specialist in equine internal medicine at Utrecht University, to discuss the high-stakes world of antimicrobial resistance (AMR) and translational medicine. We also explore the cutting-edge collaboration between Utrecht’s veterinary and human hospitals, where Mathijs is helping to validate a new sepsis diagnostic test in foals that could soon be used to save the lives of human babies. Beyond the lab, we dive into the difficult ”daily call” specialists face in antimicrobial stewardship: the challenge of ”daring to not use” antibiotics despite intense pressure from worried animal owners. From midnight clinical emergencies to research that changes international policy, Mathijs shares what it truly means to be a specialist at the intersection of animal and human health