OpenAI Podcast
OpenAI Podcast
Podcast Description
Hosted by Andrew Mayne, The OpenAI Podcast features conversations with the people building with and working at OpenAI. Topics range from how new features are developed to what users are doing with the technology. It’s a practical look at how AI is made and where it’s going, told by the people closest to the work. Hosted on Acast. See acast.com/privacy for more information.
Podcast Insights
Content Themes
The podcast covers a range of topics related to AI, including new feature development, user applications, and future trends. For example, the first episode features a discussion with Sam Altman on topics such as AGI, GPT-5, AI-powered parenting, and the implications of AI technologies on society. The show aims to provide practical insights into how AI is created and evolves.

Hosted by Andrew Mayne, The OpenAI Podcast features conversations with the people building with and working at OpenAI. Topics range from how new features are developed to what users are doing with the technology. It’s a practical look at how AI is made and where it’s going, told by the people closest to the work.
Hosted on Acast. See acast.com/privacy for more information.
AI is beginning to change how science gets done. Head of OpenAI for Science Kevin Weil and OpenAI research scientist Alex Lupsasca talk about the early signs of acceleration researchers are seeing with GPT-5—from surfacing literature across fields and languages, to speeding up complex calculations, to designing follow-up experiments. They unpack what’s possible today, what doesn’t work yet, and why the next few years could reshape the trajectory of scientific progress across physics, math, biology and beyond.
Chapters
– 00:00:40 — OpenAI for Science mission
– 00:06:00 — Literature search and intersections across fields
– 00:11:19 — A fusion physicist shows what GPT-5 can do
– 00:15:08 — GPT-5 Pro and black hole symmetries
– 00:19:02 — Getting the most out of the models
– 00:24:33 — OpenAI’s new research paper (https://openai.com/index/accelerating-science-gpt-5/)
– 00:29:59 — Looking ahead to the next 5 years
– 00:32:05 — Will predictions outpace experiments?
– 00:36:43 — The pace of model improvement
– 00:40:31 — What do scientific benchmarks look like?
– 00:44:16 — Fusion and the promise of abundant energy
– 00:48:07 — Closing: Science 2.0 moment
Hosted on Acast. See acast.com/privacy for more information.

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