The Big Brain Podcast
The Big Brain Podcast
Podcast Description
The Big Brain Podcast features conversations with crypto's most influential thinkers, builders, and traders.
Co-hosted by The Block CEO Larry Cermak and MegaETH CSO Namik Muduroglu, these interviews challenge ideas, dig into mental models, and push guests beyond the headlines.
This show isn't about predicting the future of crypto—it’s about spotlighting the big brains shaping it.
Podcast Insights
Content Themes
This podcast delves into various topics surrounding cryptocurrency, decentralized finance (DeFi), and the intersection of technology, economics, and culture. Notable episodes include discussions on the evolution of DeFi with Rune Christensen and Guy Young, focusing on its shift toward sustainable models and the economic implications of Bitcoin's future with Haseeb Qureshi and Jordi Alexander.
The Big Brain Podcast features conversations with crypto’s most influential thinkers, builders, and traders.
Co-hosted by The Block CEO Larry Cermak and MegaETH CSO Namik Muduroglu, these interviews challenge ideas, dig into mental models, and push guests beyond the headlines.
This show isn’t about predicting the future of crypto—it’s about spotlighting the big brains shaping it.
In this episode, Guy Young & Rune Christensen discuss the evolution of DeFi, noting how it has become more grounded in reality and sustainable business models, moving away from the early hype and ideological claims.
OUTLINE:
00:00 Introduction
01:23 DeFi Ain’t What it Used To Be
08:27 Ethena’s Success
13:01 Get $HYPE(D)
15:08 HL L1
16:38 ‘Ecosystem Protocols’
19:32 DeFi User Capture
21:42 DeFi Endgame
22:05 Hyper-rational Users Onchain
24:53 Compressing DeFi Rates
27:16 Stealing from the Rich
28:43Onchain KYC
30:57 Forking DeFi
33:57 The Future of Finance
37:50 ‘MicroStrategy Playbook” for Alts
42:19 Bitcoin DeFi?
43:57 F.A.F.O. Onchain
SHOW LINKS:
– Apple: https://apple.co/43F3vmq
– Spotify: https://spoti.fi/44NT1lZ
– Larry: https://x.com/lawmaster
– Namik: https://x.com/NamikMuduroglu
– The Block Podcasts: https://x.com/TheBlockPods
GUEST LINKS:
– Rune: @RuneKek
– Guy: @gdog97_
– Sky: https://sky.money/
– Ethena: https://ethena.fi/
Disclaimer
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