Pathocast in Review
Pathocast in Review
Podcast Description
The Pathocast in Review adopts a journal club format to critically dissect the latest research in immunology, virology, and infectious disease. Join our panellist as they deep-dive into recently published studies in a roundtable discussion. Leaving no stone unturned—we cover groundbreaking work across basic science, translational research, and clinical studies that are pushing the boundaries of the field.
follow us on:
Instagram - instagram.com/pathocast_review
Tiktok - www.tiktok.com/@pathocast_rev
Podcast Insights
Content Themes
The podcast primarily focuses on the latest discoveries in immunology, with episodes covering topics such as targeting precursor B cells for broadly neutralizing antibodies and the unexpected role of antibiotics in HIV prevention for uncircumcised men. Specific discussions highlight groundbreaking research from both basic science and clinical studies that impact global health strategies.
The Pathocast in Review adopts a journal club format to critically dissect the latest research in immunology, virology, and infectious disease. Join our panellist as they deep-dive into recently published studies in a roundtable discussion. Leaving no stone unturned—we cover groundbreaking work across basic science, translational research, and clinical studies that are pushing the boundaries of the field.
follow us on:
Instagram – instagram.com/pathocast_review
Tiktok – www.tiktok.com/@pathocast_rev
Welcome to Pathocast In Review – S1. Ep3 – Immune Harmony and Disruption: IgA in the Gut, and Gestational Diabetes Risks GBS. The third episode explores how secretory IgA shapes intestinal immune balance by limiting viral colonisation, and how its absence triggers a compensatory expansion of CD8 T cells. We also examine how gestational diabetes disrupts maternal immunity and alters the vaginal microbiota, amplifying the harmful effects of Group B Streptococcus colonisation during pregnancy.
Papers in Review:1. Immunoglobulin A controls intestinal virus colonization to preserve immune homeostasis (DOI: 10.1016/j.chom.2025.03.004).
2. Gestational diabetes augments group B Streptococcus infection by disrupting maternal immunity and the vaginal microbiota (DOI: 10.1038/s41467-024-45336-6).
Moderator: Wealth Okete (@wealthokete_)
Panelists: Rachael Gachogo and Nelisa Makeleni (@nelly_saciar)
Production: Zd Creations
Creator: Immun-Vir JC
Music: iLethu (@Mphephethwa_sa)
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