unNatural Selection
unNatural Selection
Podcast Description
Curious about what innovation looks like in industries vastly different from yours? The unNatural Selection Podcast applies ‘survival of the fittest’ to the world of business innovation. We explore how organizations adapt, evolve, and outcompete under the ruthless laws of evolution. In the podcast, I take a hands-on approach to talk to pioneers across industries to find out how they evolve faster than the competition—and what it really takes to thrive at their frontiers.
Podcast Insights
Content Themes
The podcast focuses on the theme of business innovation across various fields, with episodes exploring diverse topics such as sports psychology in talent development, governmental influence on genomics research, hospitality design strategies, healthcare innovation models, gaming industry transformations, NASA’s leadership in space exploration, and survival strategies in self-defense training. Specific episodes delve into how mentors shape championship mindsets in tennis, the impact of funding cuts on genomics, and the lessons learned from Kodak's resistance to digital innovation.

~ Evolution by Design: Synthesizing Cross-Industry Innovation ~
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Curious about what innovation looks like in industries vastly different from yours? The UnNatural Selection Podcast applies ‘Survival of the Fittest’ to the world of business innovation. We explore how organizations adapt, evolve, and outcompete under the ruthless laws of evolution — directly from the pioneers shaping their frontiers.
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* This podcast is a living thesis on innovation strategy. The best place to start are the Synthesis Episodes (eg Episode 25)
What if some of medicine’s biggest opportunities lie not in inventing new treatments, but in questioning what we already accept as standard practice?
Dr. Rishi Singh, Chair of Ophthalmology at Mass General Brigham and Professor at Harvard Medical School, joins Nic to explore the evolution of ophthalmology through AI, imaging, oculomics, precision medicine, and remote care.
They examine how AI can democratize expertise, how the eye can serve as a window into systemic disease, and why longitudinal data could replace “one-size-fits-all” treatment.
The deeper lesson: innovation happens when technology changes not only what we can do, but what we consider possible… and what we stop doing simply because it has always been done.

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