Second Order
Second Order
Podcast Description
Hosted by two Stanford graduate students, Neha and Elsa, Second Order explores the mental models and skills that make us better entrepreneurs. Through deep conversations with experts who’ve built, led, or studied what actually works, we go beyond the highlight reel to unpack the habits, frameworks, and decisions that drive meaningful impact. If you're building something (or thinking about it) this is your space to think a layer deeper.
Podcast Insights
Content Themes
The podcast focuses on entrepreneurial mental models, decision-making frameworks, and impactful habits, with episodes exploring storytelling's role in leadership, the utility of OKRs in startups, and the importance of vulnerability in team dynamics.
Hosted by two Stanford graduate students, Neha and Elsa, Second Order explores the mental models and skills that make us better entrepreneurs. Through deep conversations with experts who’ve built, led, or studied what actually works, we go beyond the highlight reel to unpack the habits, frameworks, and decisions that drive meaningful impact. If you’re building something (or thinking about it) this is your space to think a layer deeper.
In this episode, Dr. Derek Paul, physician-turned-founder and CEO of Glass Health, joins Elsa to discuss the mindset shift from medicine to entrepreneurship—and how clinical reasoning can shape the way we build AI. Backed by Y Combinator and Breyer Capital, Glass Health began as a digital notebook for doctors and evolved into a leading platform for AI-powered clinical decision support.
Derek explains how physicians’ structured approach to diagnosis—testing hypotheses, managing uncertainty, and learning from feedback—translates directly into effective product design and company building. He shares how Glass ensures medical accuracy and safety, what it means to train AI models with physician expertise, and how startups can navigate FDA frameworks, EHR integrations, and data compliance while maintaining speed and innovation.
From leaving the clinic to leading an AI company, Derek reflects on the cognitive frameworks that drive both good medicine and good startups—and why mastering uncertainty is the core skill behind both.
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