Near Horizon
Near Horizon
Podcast Description
We chat with AI founders about building great companies. As former entrepreneurs ourselves, we're not just investors - we work alongside our founders as true partners. Our focus is helping early-stage AI businesses, especially solo founders, tackle everything from product development to landing first customers. Join us for practical insights from the startup trenches.
Podcast Insights
Content Themes
Centers on topics relevant to early-stage AI startups, including product development, customer acquisition, and founder experiences, featuring episodes like Frank Li discussing the implications of brightfield imaging in biotech and Andrew Pannu sharing insights on competitive intelligence in BioPharma, along with specific discussions on challenges faced by solo founders.
We chat with AI founders about building great companies. As former entrepreneurs ourselves, we’re not just investors – we work alongside our founders as true partners. Our focus is helping early-stage AI businesses, especially solo founders, tackle everything from product development to landing first customers. Join us for practical insights from the startup trenches.
(2:10) Frank’s background – Stanford, Palantir, Google, Calico, now Stately Bio
(4:35) What Stately Bio does – Marrying brightfield imaging with modern ML for live cell analysis
(8:10) Why brightfield imaging matters – Cheap, live, centuries-old tech meets new machine learning
(12:05) Real-time monitoring and forecasting biological outcomes
(18:20) How living cell observation shrinks iteration cycles
(24:45) Applications to stem cell therapies: diabetes, Parkinson’s, liver, heart, kidney
(30:10) ML advantage – Machine vision finds subtle signals invisible to humans
(35:50) Stately Bio’s early success – New York Blood Center partnership
(40:25) The cost advantage of imaging vs. single-cell omics
(44:30) Platform vs pipeline – Why Stately is building therapies, not just a tool
(50:00) Future verticals: Biomanufacturing, synthetic biology applications
(54:50) Frank’s journey – From coder to founder to biotech CEO
(1:00:05) Challenges in filtering conflicting advice as a founder
(1:04:40) Surprise learnings from scaling Stately
(1:09:00) ISCT conference announcements – New breakthroughs in suspension cells imaging
(1:13:25) Big vision – Starting the phenomics revolution through live-cell analysis
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