In this episode of the Active Ingredients podcast, host Thomas Dove interviews Vladislav Makarenko, Global HR Leader at Alphasigma.

Vladislav shares his unconventional path through the life sciences industry, from achieving the head of HR role by age 32 to boldly stepping out of HR to gain firsthand business experience.

This episode explores the essential components of effective leadership through Vladislav's ”leadership triangle” framework, the importance of owning your career direction, and why self-development often represents the most challenging yet critical work a leader can undertake. His journey from the Soviet Union to global pharmaceutical companies offers unique insights into building credibility and leading across cultures.

Key Takeaways

• Discover the leadership triangle framework, comprising strategic leadership, people leadership, and decisive execution.
• Learn how to own your career direction by establishing a clear North Star and acting as if you're already in the role.
• Explore the power of seeking discomfort as a development strategy, where 6-7 out of 10 tasks should challenge you enough to ”pull your hair out”.
• Understand why stepping into the business from enabling functions like HR provides invaluable credibility and empathy when serving stakeholders in pharmaceutical and biotech organizations.
• Take away the importance of psychological investment in coaching, mentoring, and self-analysis before pursuing traditional qualifications like MBAs or professional certifications.
• Gain practical approaches for global leadership that emphasize authentic connection, servant leadership principles, and genuine care for team members across virtual environments.
• Uncover how AI can enhance human leadership by handling administrative tasks, freeing leaders to focus on empathy, coaching, and meaningful feedback conversations.
• Apply the fundamentals of outstanding leadership through empathy, asking coaching questions, providing constructive feedback, and understanding individuals' long-term career aspirations.

Snippets

• ”The CEO is normally for me, the chief people officer.”
• ”If you really mean well for the organization and for the people and for the business, try to get to a position of leadership where you can influence things in a positive way”.
• ”So whenever I felt that I was comfortable, that was a signal for me to look to fork.”
• ”Get the basics right. Feedback, constructive, open, sometimes hard but honest feedback. How often do leaders do that? Unfortunately, not that often.”

Timestamps & Topics

The following timestamps are approximations:

• 00:00 — Intro: Overview of Vladislav's unconventional career path and leadership philosophy
• 05:42 — Leadership Triangle: Strategic leadership, people focus, and decisive execution framework
• 18:33 — Career Ownership: Setting North Stars and acting as if you're already in the role
• 28:15 — Bold Moves: Leaving comfortable positions and embracing discomfort for growth
• 36:12 — Business Experience: Why HR leaders benefit from stepping into commercial roles
• 45:30 — Self-Development: The critical importance of psychological coaching and mentoring
• 52:18 — Global Leadership: Leading authentically across cultures and virtual environments

Resources

• Follow Vladislav Makarenko on LinkedIn: https://www.linkedin.com/in/vlad-makarenko-global-hr/

• Follow Thomas Dove on LinkedIn: https://www.linkedin.com/in/lifesciencesexecutivesearch/

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