TTS Pulse Podcast
TTS Pulse Podcast
Podcast Description
🎙️ TTS Pulse Podcasts – Brought to you by the TTS Education Committee, this podcast series delivers the latest insights, innovations, and inspiration from across the transplant world. Tune in for expert interviews, trending topics, educational highlights, and everything you need to know now in transplantation. From the cutting edge to the everyday, TTS Pulse keeps your finger on the pulse of what's happening.
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Content Themes
The podcast focuses on various topics relevant to the transplant community, including disease prevention strategies, clinical advancements, and patient care. Recent episodes have covered critical issues such as Measles Risk Reduction Strategies for transplant patients, exploring clinical features and prevention methods in the context of current epidemiological trends.
🎙️ TTS Pulse Podcasts – Brought to you by the TTS Education Committee, this podcast series delivers the latest insights, innovations, and inspiration from across the transplant world. Tune in for expert interviews, trending topics, educational highlights, and everything you need to know now in transplantation. From the cutting edge to the everyday, TTS Pulse keeps your finger on the pulse of what’s happening.
David K.C. Cooper discusses the recent publication “The Relative Roles of Inflammation in Kidney Allotransplantation and Xenotransplantation”
The nature and severity of the inflammatory response influences the outcome of organ allotransplantation and xenotransplantation. In allotransplantation, the source of the allograft, for example, from a living, brain-dead, or circulatory death donor, influences the inflammatory response, as do such factors as the preexisting comorbidities and the length of the period of chronic kidney disease in the recipient and the management he/she has received. There is also inflammation associated with the transplant surgery, for example, as a result of ischemia-reperfusion injury. In xenotransplantation, inflammation associated with donor factors will be reduced and, as the patients will receive a pig graft at a much earlier stage of their chronic organ failure, the contribution of recipient factors should also be reduced. However, there is a well-documented systemic inflammatory response to the presence of a pig xenograft (probably associated with species molecular differences) that plays a role in activating the innate immune response. Indeed, there is a complex interaction between inflammation, coagulation dysfunction, and the innate and adaptive immune responses. Suppression of the inflammatory response, for example, by interleukin-6 receptor blockade, would appear to be beneficial after xenotransplantation. Several biomarkers of inflammation have been identified that may be valuable in assessing the response to therapy.
Read the publication:
https://journals.lww.com/transplantjournal/fulltext/9900/the_relative_roles_of_inflammation_in_kidney.1173.aspx
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About the Journal
The official Journal of The Transplantation Society. Transplantation (https://transplantjournal.com) is published monthly and is a highly cited and influential journal in the field, with more than 25,000 citations per year.
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The Transplantation Society – Learn more about our journla:
https://tts.org/journal/transplantation-journal
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