In Episode 7 of The Orange T, host Stephen M. Perry sits down with life sciences leader Nicholas Mandala to explore the forces reshaping drug development, pharmaceutical manufacturing, and healthcare innovation.

From artificial intelligence in early drug discovery to robotics in aseptic manufacturing, the conversation explores how emerging technologies are accelerating scientific progress across the life sciences industry.

Nick explains why AI – at the intersection of product and regulated spaces – is transforming molecular discovery, while still requiring a “human in the loop” to ensure quality, safety, and regulatory confidence. The discussion also examines how other industries like semiconductors may be decades ahead in automation, and what pharma can learn as billions of dollars flow into new manufacturing infrastructure.

A broad sweeping discussion and dive into major industry shifts including:

• The post-pandemic rebound in innovation
• The upcoming pharmaceutical patent cliff
• The rise of combination products and advanced drug delivery system
• The growing role of digital health and connected therapies

For scientists, engineers, and life sciences leaders, this episode offers a thoughtful look at how technology, leadership, and innovation are converging to shape the next era of healthcare.

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Recorded at Kymanox HQ in Research Triangle Park, North Carolina.