Most GI protocols lean on the “Core Four,” yet some of our biggest clinical wins come from solutions that defy standard categories. This episode spotlights those outliers—supplements that enhance motility, fine‑tune the gut’s immune terrain, and fortify barrier integrity whether used solo or layered into broader protocols. Our panel shares when they reach for these stand‑alone staples, practical dosing pearls, and pitfalls to avoid. If you feel your digestive toolkit is missing a key piece, these category‑benders could be the game‑changers you need.