Gizem Yağız is a General Partner at 212 NexT, a venture capital fund focused on advanced materials and deep tech investments. Backed by industrial leaders like Akök Holding, 212 NexT invests globally in early-stage startups building breakthrough technologies across chemicals, advanced materials, and circular systems. In this episode, we explore how deep tech investing actually works—and why it requires a different playbook than traditional software VC.00:07 – Introduction to TRVC & Gizem Yağız00:33 – What is 212 NexT01:09 – Early career in M&A (RWE / Thames Water)02:43 – Moving to Turkey: Pragma Corporate Finance04:30 – Key lesson: you don’t need to know everything06:01 – The “puzzle solving” nature of M&A07:14 – Transition to IFC09:34 – First exposure to venture (Earlybird investment)10:59 – Founding story of 212 NexT11:52 – Role of Akök Holding14:43 – What “advanced materials” investing means16:00 – Sustainability vs unit economics17:54 – Fund strategy and deployment18:34 – Deal flow: analyzing 1,200 startups19:41 – Why Turkey is a bridge for deep tech22:29 – Strategic exits vs IPOs24:48 – Why deep tech requires patience27:38 – Why deep tech becomes defensible over time28:34 – Case studies: Haelixa & Aepnus32:31 – What drives Gizem: building “1 + 1 is more than 2” outcomes34:06 – Why deep tech founders need more than capital35:58 – How 212 NexT adds value (beyond writing checks)37:10 – Building technical conviction without being technical founders39:41 – Why Turkey still lacks deep tech success stories (and what’s missing)40:45 – Why Turkey lacks deep tech success stories (yet)41:02 – Importance of incentives and non-dilutive funding42:06 – Comparison with European funding (EIC)43:01 – Structural challenges in Turkey’s deep tech ecosystem45:29 – Book recommendations and closing thoughts🔗 Referenced (Companies & Organizations)212 NexT – https://212.vc212 – https://212.vcAkök Holding – https://www.kokholding.comAksa Akrilik – https://www.aksa.comIFC – https://www.ifc.orgEarlybird (now BEK ventures) – https://www.bekventures.com/European Innovation Council – https://eic.ec.europa.euETH Zurich – https://ethz.chHaelixa – https://haelixa.com/ Aepnius – https://www.aepnus.com/📚 Recommended BooksStories That Stick – Kindra Hall (https://www.amazon.com/Stories-That-Stick-Storytelling-Captivate/dp/140021193X)The Four Agreements – Don Miguel Ruiz (https://www.amazon.com/Four-Agreements-Practical-Personal-Freedom/dp/1878424319)