Optimize We by Lindsay O'Neill
Optimize We by Lindsay O'Neill
Podcast Description
Tired of the wellness industry’s confusing, overwhelming, and often ineffective information? Optimize We, hosted by TEDx speaker and biohacking entrepreneur Lindsay O’Neill, delivers science-backed, no-BS insights to help you optimize your health and performance.As a career technologist, Harvard-certified culinary medicine chef, founder of Small Hinges Health, and a featured expert in Women’s Health Magazine, Forbes, Crain’s NY, MSN, and NY Weekly Magazine, Lindsay cuts through the noise with a data-driven approach to longevity and human optimization.Expect powerhouse guests like Jesse Itzler (NYT Best-Selling Author), Lavinia Errico (Equinox Co-founder), and Brian Sanders (Food Lies). Each episode delivers expert insights, transformational stories, and unpacks real solutions—no gimmicks, no fluff, just actionable strategies to address your bio-individual needs and optimize your health.Brought to you by Wellness Eternal, creators of The Biohacking Directory—the “Yelp of Biohacking.” Ready to separate fact from fiction? Tune in and optimize We together.
Podcast Insights
Content Themes
The podcast focuses on health optimization, biohacking, and wellness with episodes that cover topics like ancestral nutrition practices, mental health and movement integration, and the impact of chronic inflammation on well-being. For instance, episodes include discussions around the journey of personal health stories alongside expert insights in areas like hormonal changes and fitness innovation.

Tired of wellness information that is confusing, overwhelming, and too often useless? What works? What is safe? Who can you trust?
Lindsay "LOO" O'Neill-O'Keefe learned the hard way. At the height of her tech career, she was hit by a car while seven months pregnant. The health issues that followed, for her and her daughter, sent her on a frustrating search for the right providers and the right solutions. The lesson: health is wealth, but only if you know who and what to trust.
Now a global entrepreneur, speaker (TEDx, Gaia, and the U.N.), Harvard-certified culinary medicine chef, career technologist, contributor to Entrepreneur, TopDoctor and other leading magazines, Lindsay sits down with the physicians, scientists, and wellness experts shaping the future of longevity.
Every episode is a fast, focused 15 to 20 minute interview: what makes this expert different, which solutions they swear by, and which ones they would never recommend. No rambling. No gimmicks. No fluff.
Built by experts, for experts… and for anyone serious about optimizing their own health. Guests include Kashif Khan (founder of The DNA Company), Lavinia Errico (co-founder of Equinox), and many more.
Formerly Optimize W(e), The Wellness Index Podcast is brought to you by Wellness Eternal, creators of The Wellness Index Report, a monthly ranking of expert-nominated wellness solutions published out to 1.2 billion people worldwide.
At Wellness Eternal, first W(e) verify, then W(e) amplify.
*The views and opinions shared on this podcast are those of the guests and host and have not been evaluated by the FDA. This content is for informational purposes only and is not medical advice. Consult your physician before starting any new health protocol, supplement, or treatment.
The Optimize W(e) Podcast is back with a new name and a sharper mission. Relaunched in 2026 as The Wellness Index Report Podcast, this is peer-to-peer insight for providers: what's working, what isn't, which wellness solutions actually move the needle on patient outcomes, and which ones are sitting in the corner collecting dust.
Each week, Lindsay "LOO" O'Neill-O'Keefe sits down with experts across health and wellness to pair cutting-edge science and technology with decades of research and real in-clinic practice.
New episodes weekly, 15 to 20 minutes. If you're a provider who wants to save time, energy, and headaches, tune in.

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