Join host David Oliva from Organomation for an in-depth conversation with Sean Orlowicz, Principal Marketing Development Manager at Phenomenex, about the analytical challenges and innovative solutions for GLP-1 peptide therapeutics like semaglutide and tirzepatide.In this episode, presented in collaboration with Separation Science (https://www.sepscience.com/)—a premier learning platform for analytical scientists—Sean shares over 22 years of chromatography expertise covering critical topics including:Key Discussion Topics:- Unique analytical challenges in separating GLP-1 analogues and related impurities- Column selectivity and efficiency optimization for complex peptide separations- The role of Aeris Peptide XB-C18 and core-shell particle technology- Method robustness, transferability, and regulatory considerations for sterile injectables- Size exclusion chromatography for aggregate analysis- High-resolution mass spectrometry applications in peptide analysis- Preparative chromatography for API purification at commercial scale- Common pitfalls and troubleshooting tips for peptide method development- The genericization of GLP-1 therapeutics and global market trendsAbout the Guest:Sean Orlowicz brings extensive experience from both laboratory and global pharmaceutical market perspectives at Phenomenex, specializing in peptide analysis workflows from API manufacturing to analytical testing.This episode is brought to you in collaboration with Separation Science, the leading online educational platform providing chromatographers with expert tutorials, webinars, application notes, and learning modules across LC, GC, MS, and separation technologies.Special thanks to Phenomenex for their continued innovation in developing chromatography solutions that advance pharmaceutical analysis, including specialized columns and methods for GLP-1 peptide therapeutics.Resources Mentioned:- Phenomenex GLP-1 Applications Notebook- Biozen dSEC-1 SEC columns for aggregate analysis- Technical notes on semaglutide and tirzepatide analysis- Visit www.phenomenex.com for application support- Explore www.sepscience.com for chromatography education and trainingRelevant for: Analytical chemists, pharmaceutical scientists, method development specialists, HPLC/UHPLC users, peptide researchers, quality control professionals, and separation scientists working in biopharma, generic pharmaceuticals, and regulatory environments.#Chromatography #GLP1 #PeptideAnalysis #HPLC #Semaglutide #Phenomenex #SeparationScience #AnalyticalChemistry #MethodDevelopment #Pharmaceuticals