Melanoma Matters
Melanoma Matters
Podcast Description
From the UK to the USA - Melanoma Matters is on a mission!
Hosts James Larkin and Sapna Patel are spreading the word on melanoma, one podcast at a time. Tune in for a critical review of the literature and a discussion of how we incorporate the data into our practices...across the pond(s).
#MelanomaMatters video podcast
Podcast Insights
Content Themes
The podcast covers a wide range of melanoma-related topics, including immune therapies, clinical trial results, and updates from major medical conferences. Notable episodes examine studies like the CheckMate 067 and the implications of the ADAPT-IT study on treatment strategies, alongside discussions about patient care and systemic challenges in accessing effective therapies.
From the UK to the USA – Melanoma Matters is on a mission!
Hosts James Larkin and Sapna Patel are spreading the word on melanoma, one podcast at a time. Tune in for a critical review of the literature and a discussion of how we incorporate the data into our practices…across the pond(s).
#MelanomaMatters video podcast
You wanted it, we gave it… best of ASCO …colon…2025 :D
In this episode, hosts James and Sapna discuss the key highlights from ASCO 2025, focusing on significant abstracts related to melanoma treatment. They delve into the implications of adrenal insufficiency, the 5 year, final results of Lifileucel, and the ongoing debate between neoadjuvant and adjuvant therapies. The conversation also explores the role of IL-6 in treatment efficacy and the importance of understanding sentinel lymph node positivity. The hosts emphasize the need for innovative clinical trial designs to adapt to emerging data and improve patient outcomes.
Keywords
ASCO 2025, melanoma, neoadjuvant therapy, adrenal insufficiency, lifileucel, immunotherapy, clinical trials, IL-6, treatment outcomes, cancer research
Chapters
00:00 Introduction and Overview of ASCO 2025
03:16 DoorDash!
05:43 Key Highlights from ASCO 2025
08:29 Lifileucel and Its Impact on Treatment
10:53 Long-term Outcomes and Toxicity Considerations
15:49 Exploring Treatment Efficacy in Refractory Populations
17:41 Neoadjuvant and Adjuvant Therapies: A Comparative Analysis
21:07 Investigating GM-CSF’s Role in Mitigating Toxicity
22:36 RELA 098: Insights and Implications
25:37 Understanding Sentinel Lymph Node Positivity in Melanoma
26:34 Future Directions in Neoadjuvant Therapy Research
36:18 Fact Check
38:17 Discussion on IPI GM-CSF and Adrenal Insufficiency
42:09 Impact of Adrenal Insufficiency on Patients
45:06 Future Directions in Neoadjuvant Trials
47:26 Wrap-Up and Reflections
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