APS Publications Podcast
APS Publications Podcast
Podcast Description
Listen to author interviews, commentaries from thought leaders, and insightful discussions about important topics in physiology and scientific publishing. Brought to you by the American Physiological Society (APS) Publications.
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The podcast covers significant themes such as mental health in education, inclusive teaching methods, engaging learning techniques, and critical thinking skills in physiology. Specific episodes include discussions on instructors revealing personal mental health struggles to enhance student experiences, the impact of Scientist Spotlight assignments on student inclusion, and the use of digital tools to enhance learning in a post-COVID context.
Listen to author interviews, commentaries from thought leaders, and insightful discussions about important topics in physiology and scientific publishing. Brought to you by the American Physiological Society (APS) Publications.
In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, author Periklis Marnas discusses inhalation exposure of adult D. melanogaster to cigarette smoke and changes in physiological parameters and the expression of COPD-associated orthologous genes. The study found that transcriptomic responses were more profound in females, indicating sex-specific responses to inhaled toxicants. Furthermore, enrichment analyses of the differentially expressed genes in females pointed to biomolecules associated with response to nicotine and detoxification. D. melanogaster thus provides a powerful model system to test the efficacy of new potential drugs for COPD treatment.
Marnas P, Lüpold S, Giannakou L, Giannopoulos AS, Hatzoglou C, Gourgoulianis KI, Zarogiannis SG, Rouka E. Modeling COPD in Drosophila melanogaster by cigarette smoke inhalation: functional changes and alterations in the expression of COPD-relevant orthologous genes. Am J Physiol Regul Integr Comp Physiol. 2025 Jul 1;329(1):R13-R19. https://doi.org/10.1152/ajpregu.00056.2025
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