Alzheimer’s Breakthrough with Dr. Josh Helman, MD
Alzheimer’s Breakthrough with Dr. Josh Helman, MD
Podcast Description
Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health.
Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope.
If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.
Podcast Insights
Content Themes
The podcast focuses on critical topics surrounding Alzheimer’s prevention and reversal, covering themes such as lifestyle interventions, emerging research in neurodegeneration, and personal health journeys. Episodes include discussions on the role of diet, toxicity in common items like coffee, and the science of brain health longevity, providing listeners with actionable advice for cognitive improvement.

Welcome to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, the transformative podcast that delves into the root causes of cognitive decline and provides real solutions for preventing—and even reversing—Alzheimer’s. Hosted by Dr. Josh Helman, MD, a Harvard-trained physician with advanced degrees in biochemistry, this show is designed for individuals living with Alzheimer’s, their loved ones, and anyone determined to preserve and improve brain health.
Each week, Dr. Josh demystifies the complexities of dementia, unpacks the latest breakthroughs in neurodegenerative research, and shares actionable lifestyle strategies drawn from his six years of clinical experience reversing Alzheimer’s. From tackling nutritional deficiencies and toxin exposure to exploring cutting-edge diagnostics and mind-body interventions, Alzheimer’s Breakthrough with Dr. Josh Helman, MD, turns every challenge into an opportunity to reclaim cognitive vitality and hope.
If you’re ready to discover evidence-based approaches that can restore mental clarity and empower you or your loved ones, tune in to Alzheimer’s Breakthrough with Dr. Josh Helman, MD, on Spotify, Apple Podcasts, or YouTube. Get ready to embrace a brighter future—one breakthrough at a time.
What if Alzheimer’s isn’t just one disease but a family of diseases? In this episode, I’m thrilled to be joined by Dr. Melissa Murray, a professor of neuroscience at the Mayo Clinic. Dr. Murray’s groundbreaking research focuses on Alzheimer’s, dementia with Lewy bodies, and other neurodegenerative conditions. She leads the Mayo Clinic’s Translational Neuropathology Lab, where her team combines neuropathology, neuroimaging, and genetics to understand these diseases better.
Dr. Murray is one of the recent winners of theRainwater Prize for Outstanding Innovation in Neurodegenerative Research, which came with a $400,000 prize to further her and her colleague Dr. Dennis Dickson’s research at Mayo Clinic.
The Rainwater Prize honors scientific contributions to the field of neurodegenerative research that focus on diseases associated with the accumulation of tau protein in the brain, with the goal of translating discoveries into meaningful therapeutic and diagnostic innovations.
Today’s discussion tackles a critical issue in brain health: treating Alzheimer’s like it’s a single disease. With advances in neuroimaging and biomarkers, we can now diagnose Alzheimer’s while people are still alive, which is a huge step forward from the past. Dr. Murray also highlights how brain donation is helping researchers like her gain deeper insights into the causes and progression of Alzheimer’s.
“We can’t help our genetics. We’re blessed with what we were given, but we also get to play that deck of cards that we’re handed, and we have a chance to make a difference.”
~ Melissa Murray, PhD
In this Episode
03:47 – The power of neuroimaging and biomarkers for early Alzheimer’s detection
05:58 – Alzheimer’s disease is not a single condition
06:54 – Understanding vascular contributions to Alzheimer’s in younger patients
12:20 – How lifestyle and genetics influence Alzheimer’s development
13:32 – The future of Alzheimer’s diagnostics: Imaging modalities
20:15 – Brain research and the role of brain donation in advancing research
40:37 – Studying the brain for infection (viruses, bacteria, or parasites)
49:44 – The connection between sleep and the risk of developing Alzheimer’s
57:51 – Ongoing research about Alzheimer’s and brain health
1:00:18 – Key takeaways from the discussion
Resources:
– Top Supplements for Alzheimer’s Guide – https://bit.ly/drjoshguide
– Book: The Tale of the Dueling Neurosurgeons by Sam Kean – https://www.amazon.com/dp/0316182354
– MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies – https://pmc.ncbi.nlm.nih.gov/articles/PMC3812105/
Connect with Melissa Murray, PhD:
– LinkedIn –https://www.linkedin.com/in/melissa-e-murray-012a919/
– Website – https://www.mayo.edu
Connect with Dr. Josh Helman, MD:
– Instagram – https://www.instagram.com/greenbrainsMD
– Facebook – https://www.facebook.com/greenbrainsmd/
– LinkedIn – https://www.linkedin.com/in/doctorjosh
– TikTok – https://www.tiktok.com/@greenbrainsmd
– YouTube – https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1
– Others – https://linktr.ee/greenbrainsmd
Disclaimer:Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

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